Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the cure of numerous myeloma. Its synthesis or review is very important for guaranteeing the purity and security of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound during the synthesis of imatinib, a drug that targets distinct varieties of most cancers, like chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the production approach and ensuring large purity.
Lapatinib Intermediate (CAS NO. Cb 7598 231278-eighty four-5): Lapatinib is utilised to take care of breast cancer, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Utilized in the procedure of breast cancer. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers which include ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy 3 drug used in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have various apps, including antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved with the synthesis of assorted gluconic acid derivatives, which happen to be Employed in foods, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication employed to manage form 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).